![]() ![]() (ii) The histologic and immunophenotypic differential diagnosis of this variant during the subacute phase includes lichen nitidus. Toe rash: Also referred to as COVID toes, this type of. The legs are the most commonly impacted area. (i) Pinpoint papular variant of PMLE is a distinct entity, which shows characteristic histology corresponding to the clinical course of the disease (acute and subacute). Pinpoint spots: This type of COVID-19 rash consists of dark pinpoint spots. ![]() Immunohistochemical stains revealed the following results: CD8, CD68 positive, CD4 variable (strongly positive to negative) and S-100 negative. The histologic differential diagnosis included lichen nitidus. Overlying epidermal atrophy with adjacent spongiosis, exocytosis, oedema and a superficial perivascular lymphocytic infiltrate and parakeratosis was also observed. Histology of the pinpoint lesion showed a nodular collection of lymphocytes and histiocytes with claw-like extension of epidermal rete ridges at the lateral boundaries of the lesion. Subacute: Clinically pinpoint papules with or without erythema were seen. Histology showed focal vesicle formation, spongiosis, oedema, red blood cells extravasation, and superficial and deep perivascular and interstitial lymphocytic infiltrate with occasional eosinophils. Acute: Clinically pinpoint papules and vesicles, some with erythematous base, were seen. The clinical, histologic and immunostain findings are summarized. We also performed immunohistochemistry on three cases to study the immunophenotype in PMLE. We correlated the histology with the clinical course of disease corresponding to acute and subacute disease presentation. In six patients skin biopsies were performed along with a detailed history and complete skin examination. For example, if petechiae are caused due to a bacterial or viral infection, then treating the infection itself by taking prescribed antibiotics should clear up the rashes.Polymorphous light eruption (PMLE) is the most common chronic idiopathic photodermatosis usually manifesting as a papular eruption along with several other morphological variants including a pinpoint papular variant.īetween June 1998 and August 2003, 10 PMLE patients presented to the Department of Dermatology at Henry Ford Hospital with complaints of a pruritic pinpoint papular eruption associated with sun exposure. The treatment for petechiae will depend on its underlying cause. Since petechiae can be a sign of a major underlying condition, you should waste no time and immediately consult your doctor as soon as you observe them. ![]() He may also ask about the other symptoms you have experienced, your recent injuries, and your medical history.ĭifferent classes of drugs that can lead to petechiae are: Your healthcare provider may ask you specific questions, such as the first time you noticed the pinpoint dots. If the tiny spots disappear due to the pressure, it means you do not have petechiae.īut if they do not blanch and appear just the same even under pressure, they are very likely to be petechiae.ĭiagnosing the underlying cause of petechiae involves a series of physical examinations and history of the condition. To check if a rash is petechiae, press a clear glass to the surface of the skin. Spots that usually appear in a cluster and look like a common rash.Red or purple flat spots on the skin that often show up suddenly.The most common symptoms of petechiae are as follows: With time, these small patches may start blending together and combine into larger patches. Instead of being raised on the skin like other rashes, they are flat on the skin. Petechiae can be red or purple in color and are less than 2 mm in diameter. What Causes Red Pinprick Spots on the Skin?.Keep reading to discover some easy remedies for treating petechiae on your skin. We will cover its symptoms, causes, diagnosis, treatment, and prevention. In this article, we will discuss in-depth petechiae. It occurs when blood vessels beneath the skin break and create multiple pinpoint rashes on the skin. The pinpoint red dots on the skin are caused due to a condition called petechiae. ![]()
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